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Surgery May Improve Survival in Patients with Rare Bladder Cancer

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Surgery May Improve Survival in Patients with Rare Bladder Cancer

Bladder neuroendocrine carcinoma (BNEC) is a rare and aggressive type of bladder cancer. Because it is uncommon, there is little agreement on the best treatment. Doctors often use chemotherapy or radiation, but the role of surgery has not been clear.

A new study looked at over 2,400 patients with BNEC from a large cancer database in the United States. Researchers compared patients who had surgery to remove the bladder with those who did not. The no-surgery group often received radiation, while the surgery group was more likely to receive chemotherapy.

The results showed that surgery was linked to better survival. Patients who had surgery lived longer overall and also lived longer without dying from bladder cancer. This benefit was especially strong for patients in the early stages of the disease (stage I and II). In these patients, surgery clearly improved long-term outcomes. For patients with advanced cancer, surgery did not provide the same survival advantage.

When surgery was combined with chemotherapy, survival improved even further. This suggests that a combined treatment approach may help some patients live longer.

For people with early-stage BNEC, surgery should be carefully considered as part of treatment planning. For advanced cases, doctors may still rely more on chemotherapy and radiation, but research continues to find better strategies.

This study gives new hope to patients with this rare bladder cancer by showing that surgery can make a real difference in certain situations. Patients should discuss with their doctors whether surgery might be an option for them.

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