WhatsApp

Does an Incomplete Endometrial Biopsy Increase the Risk of Uterine Cancer?

You are here >> Home > Latest Updates > Uterus Cancer > Does an…

Risk of endometrial cancer after insufficient endometrial biopsy a retrospective cohort study. DOI- 10.1016j.ajog.2025.06.015

When doctors need to check for problems in the uterus lining, they often take a small tissue sample called an endometrial biopsy. But sometimes, the sample doesn’t have enough tissue to make a clear diagnosis. This is called an β€œinsufficient biopsy.”

A new study looked at over 80,000 people in Denmark who had this test. About 17% had an insufficient result. The study followed these patients for four years to see who developed endometrial (uterine) cancer.

People with insufficient biopsies had a higher risk of cancer than those with normal results. But once age was taken into account, the risk was only slightly higher. That means age may play a big part in cancer risk, no matter the biopsy result.

Still, the study showed that getting a follow-up test is important. Nearly half of those with an insufficient result had another biopsyβ€”and some of those follow-ups found cancer.

If your biopsy didn’t have enough tissue, talk to your doctor about next steps. A second test could give you peace of mindβ€”or catch something important early.

Rate this post
dr swati shah - uro & gynec cancer surgeon
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.